Six year old Isabel Celis’s remains have been located. She has been missing since April 21st, 2012,

Isabel Celis’ remains have been found in rural Pima County and were later relocated to Bode Cellmark Forensics in Virginia where DNA evidence was confirmed.

While police never named any suspects they said they found “suspicious circumstances around a possible entry point” in the home.

After 18 months of Celis missing, police and volunteers conducted an exhaustive search, going as far as a door to door attempt to find the six year old.

The tragic story began when Isabel Celis’ father, Sergio Celis, went to wake Isabel up for a baseball game, and she wasn’t in bed. She wasn’t in her room or anywhere to be found.

Becky Celis, Isabel Celis mother, had already left for work an hour prior, leaving Sergio to call authorities.

Police spent the next several weeks interviewing neighbors, checking surveillance videos of nearby businesses, canvassed parks and even a local landfill.

During one of the interviews with a neighbor, she said she heard dogs barking and male voices outside her bedroom window at about 6:30am on the day Isabel was reported missing.

The neighbor also said that there were no signs that indicated a struggle.

About a month after Celis’ disappearance, police revealed Sergio Celis was barred from having any contact with Isabel Celis’ two older brothers for a period of time, with an unknown reason of why.

“That was my main hope when everything revamped, that hopefully they’ll go in a more appropriate direction that they weren’t looking at from the beginning,” he said.

Five years after Isabel Celis was reported missing and the family still has no answers, but kept their hope.

“This is not the ending that any of us hoped for, but it is also not the ending of the case,” Tucson Police Chief Chris Magnus told reporters, according to Fox 17.

Isabel Celis’ search triggered one of the largest searches for a missing child in Arizona’s history. Immediately after Isabel had vanished, more than 100 law enforcement officials including FBI and U.S. Marshals began to search for her.

Isabel had been described as a happy go lucky child who liked to wear her hair in braids and had two missing teeth.

Tucson police said at the time that they believed she was kidnapped from her home, citing a broken screen they found in her bedroom.

A bedroom window that was closed the night before the disappearance was found open the next morning, the family said in a police report. The window’s screen was damaged and on the ground.

“We have a window that was opened and a screen removed,” then-Tucson Police Chief Roberto Villasenor said in 2012, according to CNN.

“We’re labeling it as suspicious circumstances and a possible abduction,” Villasenor said.